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Best Pain Relief for Arthritis: A Doctor’s Guide

Best Pain Relief for Arthritis: A Doctor’s Guide

Written by Dr. Khosa | GP & Pain Management Physician (Registered in Ireland)


Arthritis stands as a leading cause of pain and disability in the United Kingdom, affecting millions and significantly impacting their quality of life. As a General Practitioner (GP) with extensive experience in managing this condition, I aim to provide a comprehensive guide on the best pain relief strategies for arthritis, tailored to the UK context. This guide will explore various approaches, including lifestyle modifications, pharmacological treatments, and supportive therapies, to empower patients in effectively managing their arthritis symptoms.

Understanding Arthritis: An Overview

Arthritis encompasses a range of conditions characterised by joint inflammation, leading to pain, stiffness, and reduced mobility. The two most prevalent forms are:


Osteoarthritis (OA): The most common type, resulting from the degeneration of joint
cartilage and underlying bone, often due to ageing or joint injury.
Rheumatoid Arthritis (RA): An autoimmune disorder where the body's immune system
attacks joint linings, causing inflammation and potential joint damage.


While both types share common symptoms, their management strategies can differ significantly

Lifestyle Modifications for Arthritis Management

1. Regular Exercise

Engaging in regular physical activity is paramount in managing arthritis. Exercise helps strengthenmuscles around the joints, maintain bone strength, and improve overall fitness. The National Institute for Health and Care Excellence (NICE) recommends tailored therapeutic exercises for all individuals with osteoarthritis, including local muscle strengthening and general aerobic fitness.

Recommended Activities:

• Low-Impact Aerobics: Activities such as walking, swimming, and cycling can enhance
cardiovascular health without placing undue stress on the joints.

• Strength Training: Building muscle strength supports and stabilises affected joints,
reducing pain and improving function.

• Flexibility Exercises: Practices like yoga and tai chi can improve joint flexibility and
balance, contributing to better mobility.

Guidelines:

• Consistency: Aim for at least 150 minutes of moderate-intensity exercise per week, as
recommended by health authorities.

• Personalisation: Consult with a physiotherapist to develop an exercise plan tailored to
individual capabilities and limitations.

• Caution: Start slowly and gradually increase intensity to avoid exacerbating symptoms.

2. Weight Management

Maintaining a healthy weight is crucial, especially for individuals with arthritis affecting weight-bearing joints like the knees and hips. Excess weight increases stress on these joints, exacerbating pain and accelerating cartilage degeneration. NICE advises that for people with osteoarthritis who are overweight or obese, weight loss can improve quality of life and physical function, and reduce pain.

Strategies:

• Balanced Diet: Emphasise a diet rich in fruits, vegetables, whole grains, and lean proteins
while limiting processed foods and sugary beverages.

• Portion Control: Be mindful of portion sizes to avoid overeating.

• Regular Physical Activity: Combining diet with exercise enhances weight loss efforts and
overall health

3. Joint Protection Techniques

Implementing strategies to protect joints can prevent further damage and alleviate pain.

Recommendations:

• Assistive Devices: Utilise tools like braces, splints, or walking aids to support and reduce
stress on joints.

• Ergonomic Adjustments: Modify workspaces and home environments to minimise joint
strain.

• Activity Modification: Avoid repetitive motions and high-impact activities that can
aggravate symptoms.

Pharmacological Treatments

Medication plays a significant role in managing arthritis pain and inflammation. It's essential to use these under the guidance of a healthcare professional to balance efficacy with potential side effects.

1. Paracetamol
Often considered for mild to moderate pain relief, paracetamol is available over the counter and can be effective when taken appropriately. However, its effectiveness varies among individuals, and it may not be sufficient for more severe pain.
Dosage:
• Standard Adult Dose: 500 mg to 1,000 mg every 4 to 6 hours, not exceeding 4,000 mg in
24 hours.
Considerations:
• Safety: Generally well-tolerated when used as directed.
• Limitations: May be less effective for inflammatory pain compared to other options.
2. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are commonly used to reduce inflammation and alleviate pain in arthritis patients. They are available in both oral and topical forms.
Topical NSAIDs:
• Application: Applied directly to the affected joint, suitable for superficial joints like knees
and hands.
• Benefits: Lower systemic absorption reduces the risk of gastrointestinal side effects.
• Examples: Diclofenac gel, ibuprofen gel.
Oral NSAIDs:
• Usage: Reserved for cases where topical treatments are insufficient.
• Considerations: Long-term use can lead to gastrointestinal issues, cardiovascular risks, and kidney problems. Co-prescription with proton pump inhibitors (PPIs) may be necessary to protect the stomach lining.
3. Opioids
For severe pain unresponsive to other medications, opioids like codeine may be considered. Due to the risk of dependency and side effects such as drowsiness and constipation, their use is typically limited to short-term management under strict medical supervision.
4. Capsaicin Cream
Application:
• Frequency: Applied 3 to 4 times daily.
• Initial Sensation: May cause a mild burning or tingling sensation initially, which typically
diminishes with continued use.
• Best Suited For: Osteoarthritis of the hands and knees, where topical application is easy
and effective.
Considerations:
• Avoid contact with eyes and mucous membranes.
• Wash hands thoroughly after application or use gloves.
• Benefits may take several days of regular use to become noticeable.
Exploring Topical Alternatives: Hemp Creams and Natural Options

As more patients seek natural and drug-free alternatives to traditional pharmaceuticals, topical=creams have become a growing area of interest in arthritis care. One such option gaining considerable attention is hemp cream for arthritis pain.

5. Hemp Creams for Joint and Muscle Pain Relief


What Are Hemp Creams?
Hemp creams are topical products made from hemp seed extract, often blended with essential oilsand other botanicals such as arnica, menthol, camphor, or lavender. These creams are applied directly to painful areas, delivering targeted relief to joints, muscles, and surrounding tissues.
Do Hemp Creams Really Help Arthritis Pain?
There is increasing anecdotal and emerging clinical evidence that hemp-based creams can provide effective relief for joint stiffness, inflammation, and musculoskeletal discomfort. These creams work in part by interacting with the body's endocannabinoid system (ECS), which regulates pain perception, inflammation, and immune response.
While not classified as medicines in the UK, many hemp creams are used as Class I medical devices for joint and muscle discomfort.
Doctor’s Pick: Vitalive Hemp Cream Triple Action Formula
From my experience as a GP, one of the most promising non-prescription options I’ve seen is the Vitalive Hemp Cream Triple Action Formula. Designed for daily use, it combines hemp extract with arnica and menthol, providing a cooling sensation followed by deep tissue relief. What sets it apart is its multi-modal approach—it doesn’t just mask pain but helps address underlying inflammation, making it suitable for osteoarthritis, rheumatoid arthritis, and general joint pain.
Why Vitalive is Effective:
• Triple Active Ingredients: Hemp extract, menthol, and arnica for combined anti-
inflammatory, analgesic, and circulation-boosting effects.
• Non-Greasy, Fast-Absorbing Formula: Ideal for frequent use without residue.
• Day and Night Relief: Works well as part of a day-time mobility routine or before bedtime to reduce stiffness.
• Scientifically Developed: A trusted choice for patients seeking a trusted UK brand
and safe options.
Complementary Therapies for Pain Relief
In addition to medications and topical treatments, complementary approaches can offer added pain relief for arthritis sufferers. These strategies are particularly useful for individuals who prefer non- pharmaceutical methods or want to combine different modalities.
6. Heat Therapy
How it Works:
Applying heat increases blood flow, relaxes muscles, and reduces joint stiffness. This is particularly effective for morning stiffness in rheumatoid arthritis or osteoarthritis in colder climates.
Options Include:
• Heated Wheat Bags or Pads: Ideal for shoulder and neck joints.
• Warm Baths: Especially beneficial for multiple joint pain.
• Self-Adhesive Heat Patches: Provide portable, extended relief throughout the day.
Product Spotlight: Vitalive Hemp Heat Patches
These combine the warming benefits of heat therapy with hemp extract for pain relief. They are ideal for knee, shoulder, or back pain, offering up to 12 hours of deep, soothing warmth. These patches are also non-medicated, making them safe for long-term use.
7. Cold Therapy
When to Use:
Cold therapy is best for acute flare-ups and inflammation. It helps numb the area and reduce swelling, especially in joints that are hot and tender.
Methods:
• Ice Packs or Cold Gel Packs: Wrap in a towel to avoid skin irritation.
• Cold Water Soaks: Useful for hand or foot arthritis.
When to See a Doctor
While over-the-counter remedies and lifestyle adjustments can make a significant difference, it’s crucial to know when to seek medical advice:
• Persistent or Worsening Symptoms: If your joint pain doesn’t improve or worsens despite treatment.
• Joint Swelling or Deformity: Signs of inflammation that may require disease-modifying
treatments.
• Functional Limitations: Difficulty performing daily tasks or reduced mobility.
A GP can assess whether referral to a rheumatologist, physiotherapist, or orthopaedic specialist
is necessary. They can also explore further investigations such as X-rays or blood tests.
Prescription-Only Options for Arthritis Pain
When over-the-counter treatments are insufficient, healthcare professionals may recommend
prescription medications to manage arthritis pain and inflammation effectively.
1. Disease-Modifying Anti-Rheumatic Drugs (DMARDs)
Primarily used for inflammatory arthritis like rheumatoid arthritis (RA), DMARDs suppress the immune system to prevent joint damage.

Methotrexate: A commonly prescribed DMARD that can slow disease progression and
reduce joint damage.
Sulfasalazine and Hydroxychloroquine: Often used in combination with methotrexate for enhanced effectiveness.
Considerations:
• Regular monitoring is essential to detect potential side effects, such as liver toxicity and
blood disorders.
• It may take several weeks to months before noticeable benefits occur.


2. Corticosteroids


Potent anti-inflammatory agents administered orally or via intra-articular injections.
• Injections: Directly delivered into the affected joint to provide rapid relief during acute
flare-ups.
Considerations:
• Long-term use is generally avoided due to potential side effects, including osteoporosis and weight gain.
• Injections are typically limited to a few times per year per joint to prevent cartilage damage.

3. COX-2 Inhibitors

A subclass of NSAIDs designed to reduce gastrointestinal side effects.
Celecoxib and Etoricoxib: Commonly prescribed COX-2 inhibitors that alleviate pain andinflammation.

Considerations:

• May still pose cardiovascular risks; therefore, a thorough evaluation of individual risk
factors is necessary.

The Role of Physiotherapy and Professional Rehabilitation

Physiotherapy plays a pivotal role in managing arthritis by improving joint function, alleviating pain, and enhancing overall mobility.

Benefits of Physiotherapy:

• Personalised Exercise Programs: Tailored routines to strengthen muscles around affected joints, improving stability and function.
Pain Relief Techniques: Utilisation of modalities such as heat, cold, and manual therapy to reduce discomfort.
Education and Advice: Guidance on joint protection strategies and activity modification to prevent further damage.
Assistive Devices: Recommendations for supports like braces or orthotics to aid movement and reduce strain.
Accessing Physiotherapy:
• Referral through a GP or self-referral where available.
• Services may be provided within the NHS or through private practitioners.

Comparing Top Arthritis Pain Relief Treatments in 2025

The landscape of arthritis treatment continues to evolve, with several notable advancements:

1. Non-Opioid Painkillers

The introduction of suzetrigine (Journavx) offers a novel approach by targeting specific pain pathways without the addictive risks associated with opioids. Approved for acute pain management, its role in chronic arthritis pain is under investigation.
2. Antibiotic Therapy for Chronic Pain
Emerging treatments like PP353, combining antibiotics with delivery agents, have shown promise in addressing chronic lower back pain linked to spinal infections. While not directly related to arthritis, this underscores the potential of innovative therapies in pain management.


3. Topical Agents 

Advancements in topical treatments, including formulations with hemp extract, menthol, and arnica, provide targeted relief with minimal systemic side effects. These are particularly beneficial for patients seeking non-oral options.

Natural Supplements: Omega-3 and Turmeric

Natural supplements have garnered attention for their potential anti-inflammatory properties:

1. Omega-3 Fatty Acids

Found in fish oil, omega-3s may help reduce joint pain and stiffness in rheumatoid arthritis. Studies suggest they can lower disease activity and decrease reliance on NSAIDs.
Considerations:
• Consult with a healthcare provider before starting supplements to ensure appropriate dosing and to avoid interactions with other medications.

2. Turmeric (Curcumin)

Curcumin, the active component in turmeric, has demonstrated anti-inflammatory effects that may alleviate arthritis symptoms. Some studies indicate it can be as effective as NSAIDs in reducing pain and improving function.
Considerations:
• Bioavailability can be low; formulations with enhanced absorption are available.
• Quality and concentration of supplements can vary; selecting reputable brands is crucial.

Final Recommendations from a GP for Long-Term Pain Relief

Managing arthritis effectively requires a comprehensive, individualised approach:
1. Collaborate with Healthcare Providers: Regular consultations with your GP and
specialists to tailor treatment plans and monitor disease progression.
2. Adhere to Medication Regimens: Take prescribed medications as directed and report anynside effects promptly.
3. Engage in Regular Physical Activity: Incorporate exercises that enhance strength,
flexibility, and cardiovascular health.
4. Maintain a Healthy Weight: Achieve and sustain a weight that reduces stress on joints,particularly weight-bearing ones.
5. Implement Joint Protection Techniques: Use assistive devices and modify activities to
minimise joint strain.
6. Consider Complementary Therapies: Explore options like acupuncture or massage
therapy, ensuring they are performed by qualified practitioners.

FAQ"S


1. What is the best pain relief for arthritis in 2025 according to doctors?
Answer:

As of 2025, GPs recommend a multi-pronged approach for arthritis pain relief, combining topical treatments, anti-inflammatory medications, and lifestyle changes. One standout topical is the Vitalive Hemp Cream – Triple Action Formula, designed for joint pain relief, muscle discomfort, and inflammation reduction. For moderate-to-severe cases, GPs may also suggest COX-2 inhibitors, capsaicin cream, or corticosteroid injections. Physiotherapy and low-impact exercise are also essential for long-term relief.
2. What is the strongest over-the-counter cream for arthritis pain in the UK?
Answer:
In the UK, Vitalive Hemp Cream (Triple Action Formula) is gaining popularity for being one of the strongest natural hemp-based arthritis creams, combining hemp extract, arnica, and menthol for rapid relief. It’s formulated specifically for knee, hand, and back arthritis, delivering fast-acting topical support. Other strong OTC options include 5Kind Extra Strong Hemp Cream and Deep Relief Ibuprofen Gel, though they contain synthetic actives.
3. What do NHS doctors recommend for arthritis pain?
Answer:
NHS guidelines recommend a mix of non-steroidal anti-inflammatory drugs (NSAIDs), topical creams, exercise, and weight management. For long-term support, they may prescribe DMARDs (like methotrexate), COX-2 inhibitors, or steroid injections. Increasingly, doctors also recommend physiotherapy, pain education, and approved topical options like capsaicin or menthol-based creams. Many GPs are now open to natural hemp creams if used alongside conventional care.
4. Is hemp cream good for arthritis pain relief?
Answer:
Yes, hemp cream is increasingly recommended by experts for arthritis pain, especially when enriched with natural anti-inflammatories like arnica, camphor, menthol, and eucalyptus. The Vitalive Hemp Cream – Triple Action Formula is a leading example, helping to reduce joint swelling, stiffness, and muscle soreness without the side effects of oral medication. Topical hemp creams are ideal for targeted, non-invasive relief and can be used daily.
5. Can you use hemp cream and oral medication together for arthritis?
Answer:
Absolutely. In fact, GPs often recommend topical hemp creams alongside oral treatments like NSAIDs or paracetamol. This combination provides layered pain relief — oral meds address systemic inflammation, while hemp cream targets localised joint discomfort. Vitalive Hemp Cream is safe for use with most arthritis medications, but it’s always wise to consult your GP if you're on prescription drugs.
6. What are the safest natural remedies for arthritis pain?

Answer:

Some of the safest natural remedies for arthritis include:
• Topical hemp creams (e.g. Vitalive Triple Action)
• Turmeric/curcumin supplements
• Omega-3 fatty acids from fish oil
• Epsom salt soaks for sore joints
• Gentle yoga and stretching

These options are backed by growing clinical and anecdotal evidence and are often recommended as part of a holistic treatment plan. They’re especially useful for those wanting to reduce
dependence on pharmaceuticals.
7. Which arthritis cream works best for knee joint pain?
Answer:
For knee arthritis, creams need to penetrate deep into the joint area. Vitalive Hemp Cream is often preferred by users because it combines hemp extract, menthol, and arnica — all known to soothe sore, inflamed knees. Other strong options include capsaicin cream, ibuprofen gel, or salicylate-based rubs, but many of these require prescription if used long-term.


8. How does Vitalive Hemp Cream compare to 5Kind or Deep Heat for arthritis?

Answer:
Vitalive Hemp Cream stands out for its Triple Action botanical formula, combining natural hemp, arnica, and menthol. Unlike Deep Heat, which uses only synthetic heat activators, Vitalive offers warming plus anti-inflammatory relief. Compared to 5Kind, Vitalive has fewer synthetic additives and is better suited for night-time use or sensitive skin. It’s a great choice for those seeking natural yet effective arthritis relief in 2025.

9. Do topical creams for arthritis actually work?
Answer:
Yes — topical arthritis creams can provide effective pain relief, especially for mild to moderate osteoarthritis. They work by blocking pain signals or reducing local inflammation. In 2025, many users and professionals report real improvements using hemp-based topicals, capsaicin, or NSAID gels. While they don’t cure arthritis, they can significantly reduce symptoms when used regularly and correctly.
10. What is the best daily routine for managing arthritis pain?

Answer:

An ideal daily routine for arthritis pain relief in 2025 includes:
Morning: Gentle stretching, warm shower, application of topical (e.g. Vitalive Hemp
Cream)

• Daytime: Maintain movement, short walks, joint-friendly diet, painkillers if prescribed

• Evening: Apply topical again, cold compress if swollen, light stretching

• Night: Use supportive pillows, consider a magnesium bath, and relaxation techniques

This structured approach helps reduce stiffness, inflammation, and build a sense of control.